cees dekker - An Overview

2009, discovery of a whole new phenotype for germs in slim nanofluidic slits; and 1st detection of community protein buildings together DNA applying solid-point out nanopores

It had been only in the nineties though, when nanotechnology had advanced into a amount exactly where solitary molecules could be manipulated, that the primary experimental gadgets started to look.

[Laughs] ‘It had been absolutely a terrific chance! At time, I was nicely aware that it could go Incorrect Which I could become much less successful, but I just disregarded that. Curiosity has generally been my strongest driving pressure. And by chance it all labored out.’

Our function was swiftly followed up by Other individuals, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 revealed their results on transistors made out of solitary- and multi-walled carbon nanotubes in Utilized Physics Letters.

This yielded a breakthrough. Inside only some months, we had been ready to measure transportation by means of an individual solitary-walled carbon nanotube. Based on very low-temperature experiments by a brilliant PhD scholar in my team, Sander Tans (now a valued colleague and professor at Delft University of Technological know-how using an Lively study lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes were real quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.

Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes

‘In the beginning we checked out Organic methods by using a Actual physical view and acted on The idea with the applications we knew. It took a several years right before we began Doing work additional on the massive biological problems. I then started to phone it nanobiology, a expression that didn't exist at some time.

Nanopores signify an elegant and flexible Instrument to measure single molecules. We study novel detection modes with strong-state nanopores in addition to numerous approaches to measure proteins with nanopores. Tasks encompass the following:

‘You shouldn't just think of the issues of tomorrow, and also consider the questions of the working day just after tomorrow’

Dekker started off his investigation on single carbon nanotubes in 1993 when he arrange a different line of analysis to check electrical transportation via one natural molecules between nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was accomplished inside of a collaboration Together with the group of Nobel laureate Richard Smalley. STM and nanolithography procedures have been utilized to exhibit that these nanotubes are quantum wires at the single-molecule amount, with exceptional Actual physical Homes.

[fourteen] In 2005 Dekker became associated with Netherlands-wide conversations about Clever Layout, a motion that he has given that Evidently distanced himself from. Dekker advocates that science and religion will not be in opposition but can be harmonized.

Nanoscientist Cees Dekker is really an amiable and flamboyant male who appears A lot younger than the sixty two several years he truly is – fashionable Eyeglasses, psychedelic shirt, participating smile – but not one to squander time. He normally takes his time, but no more than vital.

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Strong-state nanopores have verified for being a astonishingly adaptable probe for solitary-molecule Examination of DNA. I will describe some of our recent findings – precisely DNA knots – as well as our endeavours to extend the abilities of reliable-condition nanopores even more, inside the path of single-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.